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Cancer drugs and public preferences

Last year the UK government announced the establishment of a £600 million cancer drug fund, to be spent over 3 years. This represents a minuscule amount of money compared to the NHS’s annual budget, which is in excess of £100,000,000,000. However, it demonstrates the government’s preference for expenditure on the treatment of cancer over and above other terminal diseases such as multiple sclerosis (MS). Laura Weir of the MS Society recently spoke out in opposition to this special treatment of cancer. I tend to agree with her view, but am I justified?

Public preferences

In recent years an increasing number of newspaper column inches have been dedicated to criticising NICE for rejecting expensive cancer drugs because they are not deemed cost-effective. If we believe the media then the nation is in outrage about this. The prevailing ‘ideology’ in health economics is to evaluate interventions based on the extent to which they satisfy the preferences of the public. This is done by calculating the number of QALYs gained from an intervention and assigning a monetary value to this gain. The government has now implicitly increased this monetary value for cancer drugs, making them more likely to be deemed cost-effective. If we support the use of public preferences, and if the public support extra spending on cancer, then surely we must in turn also support the fund?

Preference for cancer drugs?

The question is whether society is willing to pay more for a drug that helps cancer patients than for a drug that improves or extends the life of anybody else. Is there really a public preference for spending on cancer drugs? I suspect there is, even if this preference has been reinforced and possibly created by the media. To my knowledge there has not been any significant research in this area. If such research did show a preference then it may justify an increased willingness to pay for cancer drugs.

And what about MS?

As somebody whose life has been affected by MS, but not by cancer, I may be bias. Or not. But I believe that expenditure on drugs should be based on the benefit they provide to an individual. Presumably the preference for cancer drugs, if not completely media-driven, is down to the large number of people affected by the disease. When it comes to the amount of money to be spent at an individual level it seems illogical to allow decisions about this to be guided by prevalence. Let’s remember we are not talking about research here, but the fact that an individual with cancer will be allowed to buy expensive (read: less cost-effective) drugs, while somebody with MS will not. I believe this is wrong. But then, I believe that the use of public preferences is not ideal.

Resources are scarce and for every expenditure there is an opportunity cost. An increase in our willingness to pay for the benefits of cancer drugs, at the extreme, leads to a decrease in spending on all other health care interventions. The cancer drug fund raises many questions, not least the possibility that a QALY may no longer be a QALY but may be a cancer-QALY. I believe this is dangerous territory.

Does this issue leave you questioning public preferences? Should we be prioritising treatment for cancer? Or is this all simply a fabrication by the media?

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Posted by on December 2, 2011 in Health and its Value

 

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Paying for organs

We have recently seen the idea of buying/selling/trading organs thrust into the media spotlight (and not for the first time). There’s a lot of very poor thinking floating around in this debate, though Sue Rabbitt Roff’s recent paper, which helped fuel the flames of the new debate, is a little more useful.

A market for organs?

There are many reasons why Sue Rabbitt Roff does not propose this, and why Iran is the only country that has adopted one. Ethically the practice is, at best, dubious. At worst it is massively exploitative. Without enough regulation and administration to render it pointless, a market would be hugely inequitable and contradictory to most Western government policy; it would redistribute health from the poor to the rich. However, as heartless machines of rationality, economists tend to be more interested in what is the most efficient policy to adopt. Economists (such as Becker and Elias) have been weighing-in on this issue for a while. In their enjoyable free-marketeer rantings on the topic, the folks at Freakonomics seemingly raised ‘repugnance’ as the only argument against a market for organs. But hopefully readers of this blog are a little more informed when it comes to health economics and realise that a market for organs, like any free market healthcare system, will be massively inefficient. Market-failures (both the “this market doesn’t look how we want it to look” kind, as well as actual market failure) would abound. While the rich’s willingness to pay for organs would far exceed that of the poor, most of us would accept that their capacity to benefit from organ donation would be the same (or lower) than that of the poor. Because the rich assign a higher monetary value to their health it would be possible for there to be a net loss of health from the purchase of an organ. In a free market system organs would, presumably, go to those who can afford them (the rich), rather than those who stand to gain the most from receiving them (the sick). And we all know that the richest are rarely the sickest. To me, none of this sounds very efficient.

Another way?

In the UK the idea of a free market for health care is repugnant enough; thankfully there is little chance of a market for organs developing. However, Sue Rabbitt Roff’s paper does not suggest this. This BMJ article doesn’t really say much and is quite limited. Economists should be chomping at the bit with claims like:

“…if the standard payment [for a kidney] were equivalent to the average annual income in the UK, currently about £28000, it would be an incentive across most income levels for those who wanted to do a kind deed and make enough money to, for instance, pay off university loans.”

Rubbish. But that doesn’t matter. Her general idea – a heavily-regulated system of organ purchase by the NHS -is a feasible one. Let’s remember that here we are talking about anonymous donors and recipients – family and friend donations could remain as they are. To be equitable there could be a fixed payment from the NHS to a donor. The level of this payment should be equal to (society’s valuation of) the health gain enjoyed by the individual receiving the transplant. In a world of value-based pricing this would be the norm! A second requirement would be that the price should be greater than or equal to the loss of health-related quality of life (plus other associated costs) to the donor. This would mean that a donation could be prevented if deemed exploitative, even if against the wishes of the donor. Such a system could nicely boost the supply of organs to existing (need-based) waiting lists.

This will probably be piloted in Scotland: the land of new ideas. For me a system would have to be so heavily regulated that there would not be much point. Politicians, clinicians and academics would love a quick-fix for the problem of organ shortages, but they’ll just have to work a bit harder. People can be encouraged to donate organs in other ways; a switch from opt-in to opt-out posthumous donation being an excellent start.

What do you think? Could the sale and purchase of organs be efficient and equitable? What safeguards would need to be in place if a system was introduced?

 
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Posted by on September 3, 2011 in Markets in Health Care

 

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The well-being valuation approach: Solution or convolution?

The ‘well-being valuation method’ is a recently developed technique for valuing the effect, in monetary terms, of a health problem on an individual’s well-being. The method involves calculating the compensating variation necessary to maintain the same level of well-being after suffering from a particular health problem, and is hoped to offer a solution to the problems of revealed preference and contingent valuation methods. A recent IZA paper investigated whether there was consistency in well-being measures for valuations of different health problems. The authors find (as might be expected) that different well-being measures give very different results. This post is inspired by the paper.

Solution?

Monetary valuation of health problems is certainly a decision-makers dream. If done right it would also be a health economist’s dream. The QALY was developed as a substitute currency for health, as money was not deemed appropriate and willingness to pay and accept methods are notoriously biased, controversial and inconsistent. The well-being valuation approach has the potential to allow us to scrap this stand-in currency by using ‘The Leydon Approach‘ and aiming questions about health problems at a representative sample of the public. Using this method we can figure out the value that individuals assign to losses in well-being associated with particular health problems and can thus decide whether a particular intervention represents good value for money. This method can also, very easily, provide different values for people with different socio-demographics.

Convolution?

In calculating QALYs there is some consensus in the use of generic preference-based measures of health-related quality of life. The well-being measure that should be used in the well-being valuation approach is unclear and, as the recent IZA paper showed, different measures give different results. And besides, is this even the direction in which health economics should be heading? Wouldn’t we be better-off adapting the QALY method and possibly working harder to assign monetary values to QALYs? Using willingness to pay methods this is not something which is really possible at the moment, due to numerous methodological problems. However, this is not to say we shouldn’t still be trying to do this using different methods. There are also massive equity concerns when we start assigning monetary values to health problems, as different people value money differently; arguably not in a way that is representative of underlying preferences for health.

Personally I think that the well-being valuation approach is, in principle, a potentially great new idea for the health economics field to adopt. It seems particularly relevant to the current debate in the UK over value-based pricing. However, I have many reservations over the direct monetary valuation of health problems as they are currently carried out. I would like to see a future analysis in the literature of the implications for equity issues of using the well-being valuation approach instead of QALYs. With the piece of mind that these methods can provide equitable outcomes I feel this new method could (and possibly should) be adopted more widely.

Please provide your thoughts on this subject using the comments box below. Also, please highlight any literature relevant to this debate.

 
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Posted by on March 7, 2011 in Health and its Value

 

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